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Buspirone

TRIGGER WARNING: The following article contains references to sex and sexual activities. Care should be taken when reading the information below.

Buspirone, sold under the brand name Buspar among others, is a medication primarily used to treat anxiety disorders, particularly generalized anxiety disorder. Benefits support its short term use. It has not been found to be effective in treating psychosis. It is taken by mouth, and it may take up to four weeks for an effect.

Common side effects include nausea, headaches, dizziness, and trouble concentrating. Serious side effects may include hallucinations, serotonin syndrome, and seizures. Use in pregnancy appears to be safe but has not been well studied, while use during breastfeeding is not recommended. How it works is not clear but it is unrelated to benzodiazepines.

Buspirone was first made in 1968 and approved for medical use in the United States in 1986. It is available as a generic medication. In 2017, it was the 80th most commonly prescribed medication in the United States, with more than ten million prescriptions.

Anxiety
Buspirone is used for the short-term treatment of anxiety disorders or symptoms of anxiety. It is generally less preferred than selective serotonin reuptake inhibitors (SSRIs).

Buspirone has no immediate anxiolytic effects, and hence has a delayed onset of action; its full clinical effectiveness may require 2 to 4 weeks to manifest. The drug has been shown to be similarly effective in the treatment of generalized anxiety disorder (GAD) to benzodiazepines including diazepam, alprazolam, lorazepam, and clorazepate. Buspirone is not known to be effective in the treatment of other anxiety disorders besides GAD,[21] although there is some limited evidence that it may be useful in the treatment of social phobia as an adjunct to selective serotonin reuptake inhibitors (SSRIs).

Other uses
Sexual dysfunction
There is some evidence that buspirone on its own may be useful in the treatment of hypoactive sexual desire disorder (HSDD) in women.

Miscellaneous
Buspirone is not effective as a treatment for benzodiazepine withdrawal, barbiturate withdrawal, or alcohol withdrawal/delirium tremens.

SSRI and SNRI antidepressants such as paroxetine and venlafaxine may cause jaw pain/jaw spasm reversible syndrome (although it is not common), and buspirone appears to be successful in treating bruxism on SSRI/SNRI-induced jaw clenching.

Original source.

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Information should be used for information only. The information located above was accurate from Wikipedia at the time of publish. The information above does not replace advice from a trained medical professional. If in any doubt, seek immediate medical assistance.
 

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